O-Desmethyl-N-deschlorobenzoyl Indomethacin - CAS 50995-53-4

O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin, formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase. It has also been used in the synthesis of prostaglandin D2 receptor antagonists.

Others, COX, Prostaglandin Receptor

Immunology/Inflammation, Others, GPCR/G Protein, Neuroscience

50938

C11H11NO3

205.213

Cc1[nH]c2ccc(O)cc2c1CC(O)=O

-20°C

Ice Packs

Small Compound