O6BTG-C8-αGlu - CAS 793035-88-8

O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, it fully inhibits MGMT in HeLaS3 cells and demonstrates no cytotoxicity even at prolonged high doses (up to 20 μM) . This compound is suitable for research on MGMT-related cancers.

DNA Methyltransferase

Chromatin/Epigenetic

792939

C24H34BrN5O7S

616.525

O(CC1=CC(Br)=CS1)C2=C3C(N(CCCCCCCCO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=N3)=NC(N)=N2

-20°C

Ice Packs

Small Compound