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OARV-771 - CAS 2683008-37-7

OARV-771 - CAS 2683008-37-7

MF-0154713-01

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Product Details

  • Bioactivity

    OARV-771, a VHL-based BET degrader (PROTAC) featuring enhanced cell permeability, demonstrates DC50 values of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3, respectively [1].

  • Target

    PROTACs, Epigenetic Reader Domain

  • Related Pathways

    PROTAC, Chromatin/Epigenetic

  • CAS Number

    2682964

  • Molecular Formula

    C49H59ClN8O8S2

  • Molecular Weight

    987.62

  • SMILES

    C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCCOCCOC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC