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OB 24 hydrochloride - CAS 939825-12-4
OB 24 hydrochloride - CAS 939825-12-4
SKU:MF-0051244
Regular price
$679.17 USD
Regular price
Sale price
$679.17 USD
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Product Details
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Bioactivity
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA) . Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
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Target
ROS, Others
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Related Pathways
Others, Immunology/Inflammation
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CAS Number
939809
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Molecular Formula
C15H18BrClN2O2
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Molecular Weight
373.68
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SMILES
Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound