Obatoclax - CAS 803712-67-6

Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.

Parasite, Autophagy, Bcl-2 Family, Others

Microbiology/Virology, Autophagy, Others, Apoptosis

803639

0.9944

C20H19N3O

317.38

C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4

-20°C

Ice Packs

Small Compound