Molfinity

Ocifisertib (CFI-400945 free base) - CAS 1338806-73-7

SKU:MF-0018647-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4 (PLK4; Ki value 0.26 nM; IC50 value 2.8 nM) .
Target
PLK, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
CAS Number
1338726
Purity
0.9904
Molecular Formula
C33H34N4O3
Molecular Weight
534.65
SMILES
O=C1[C@]2([C@@H](C2)C=3C=C4C(=CC3)C(/C=C/C5=CC=C(CN6C[C@@H](C)O[C@@H](C)C6)C=C5)=NN4)C=7C(N1)=CC=C(OC)C7
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound