Oclacitinib maleate - CAS 1640292-55-2

Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members, with IC50 values ranging from 10 to 99 nM, and JAK1-dependent cytokines, with IC50 ranging from 36 to 249 nM, while not inhibiting a panel of 38 non-JAK kinases.

Tyrosine Kinases, JAK

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis, Stem Cells, JAK/STAT signaling

1640235

0.9992

C15H23N5O2S·C4H4O4

453.51

OC(=O)\C=C\C(O)=O.CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1ncnc2[nH]ccc12

-20°C

Ice Packs

Small Compound