Odafosfamide - CAS 2097713-69-2

Odafosfamide ((S) -OBI-3424) is a highly selective prodrug bi-alkylating agent activated by aldo-keto reductase 1C3 (AKR1C3) . It exhibits potent cytotoxicity in cell lines with high AKR1C3 expression. Odafosfamide demonstrates antitumor activity in various tumors with elevated AKR1C3 expression, such as liver cancer, non-small cell lung cancer, and leukemia. It is applicable for cancer research.

Dehydrogenase

Metabolism

2097642

C21H25N4O6P

460.42

P(O[C@@H](C)C1=CC(OC2=CC(C(N(C)C)=O)=CC=C2)=C(N(=O)=O)C=C1)(=O)(N3CC3)N4CC4

-20°C

Ice Packs

Small Compound