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Molfinity

Olaparib - CAS 763113-22-0

Olaparib - CAS 763113-22-0

MF-0005233-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.

  • Target

    PARP, Autophagy, Mitophagy

  • Related Pathways

    Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy

  • CAS Number

    763091

  • Purity

    >99.99%

  • Molecular Formula

    C24H23FN4O3

  • Molecular Weight

    434.46

  • SMILES

    C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound