Olutasidenib - CAS 1887014-12-1

Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) . Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Isocitrate dehydrogenase 1 (IDH1) (IC50: 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively) .

Isocitrate Dehydrogenase (IDH), Dehydrogenase

Metabolism

1887001

0.9959

C18H15ClN4O2

354.79

C[C@H](Nc1ccc(C#N)n(C)c1=O)c1cc2cc(Cl)ccc2[nH]c1=O

-20°C

Ice Packs

Small Compound