Molfinity

ON 146040 - CAS 1404231-34-0

SKU:MF-0016908-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg 200 mg

Product Details

Bioactivity
ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.
Target
PI3K, Bcr-Abl
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
CAS Number
1404197
Purity
0.9989
Molecular Formula
C24H23N7O3S
Molecular Weight
489.55
SMILES
CN1CCN(CC1)c1ccc(Nc2ncc3NC(=O)\C(Sc3n2)=C\c2ccc(cc2)[N+]([O-])=O)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound