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ONC213 - CAS 1977540-13-8

ONC213 - CAS 1977540-13-8

MF-0122672-01

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Product Details

  • Bioactivity

    ONC213, an αKGDH inhibitor, functions by hindering αKGDH activity, thus suppressing mitochondrial respiration and elevating α-ketoglutarate levels, ultimately inducing apoptosis (Apoptosis) in AML cells. It is utilized in the study of acute myeloid leukemia.

  • Target

    Apoptosis

  • Related Pathways

    Apoptosis

  • CAS Number

    1977540-13-8

  • Molecular Formula

    C23H22F2N4O

  • Molecular Weight

    408.44

  • SMILES

    O=C1C2=C(N3C(=NCC3)N1CC4=CC=C(F)C(F)=C4)CCN(CC=5C=CC=CC5)C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound