Oncocin - CAS 1235497-90-1

Oncocin is an antibacterial peptide classified under proline-rich antimicrobial peptides (PrAMPs) . It is effective against Gram-negative bacteria, exhibiting a minimum inhibitory concentration (MIC) range of 0.125-8 μg/mL for 34 clinical isolates and strains of Enterobacteriaceae and non-fermentative bacteria. Oncocin interacts with the substrate-binding domain of the chaperone protein DnaK, with a dissociation constant in the micromolar range. This interaction results in protein misfolding and aggregation, ultimately causing bacterial cell death.

Antibacterial

Microbiology/Virology

1235497-90-1

C109H177N37O24

2389.8

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-20°C

Ice Packs

Peptide