OncoFAP-GlyPro-MMAE - CAS 2688118-55-8

OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. It is composed of the FAP ligand OncoFAP, a microtubule inhibitor (MMAE), and a linker. OncoFAP-GlyPro-MMAE can be utilized in cancer research, including studies on renal cancer.

Others, Microtubule Associated

Cytoskeletal Signaling, Others

2688055

C102H141F2N19O27S

2135.38

C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C(NC(CCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSC4C(=O)N(CCCCCC(NCC(=O)N5[C@H](C(NC6=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N7[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C8=CC=CC=C8)C)=O)C)OC)(CCC7)[H])OC)[C@H](CC)C)C)=O)[C@H](C)C)=O)[C@@H](C)C)C)=O)C=C6)=O)CCC5)=O)C(=O)C4)C(O)=O)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)=CC=C3)N=CC2

-20°C

Ice Packs

Small Compound