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Molfinity

ONO-0300302 - CAS 856689-51-5

ONO-0300302 - CAS 856689-51-5

SKU:MF-0000478-01

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  • Bioactivity

    ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h.

  • Target

    LPL Receptor, Others

  • Related Pathways

    Others, GPCR/G Protein

  • CAS Number

    856689-51-5

  • Molecular Formula

    C29H35NO5

  • Molecular Weight

    477.59

  • SMILES

    COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound