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ONO-0300302 - CAS 856689-51-5
ONO-0300302 - CAS 856689-51-5
SKU:MF-0000478-01
Regular price
$1,980.50 USD
Regular price
$1,430.00 USD
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$1,980.50 USD
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Product Details
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Bioactivity
ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h.
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Target
LPL Receptor, Others
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Related Pathways
Others, GPCR/G Protein
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CAS Number
856689-51-5
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Molecular Formula
C29H35NO5
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Molecular Weight
477.59
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SMILES
COc1cc(cc(OC)c1C)[C@@H](O)[C@@H](CC1Cc2ccccc2C1)Cn1ccc(CCC(O)=O)c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound