ONO-8711 - CAS 216158-34-8

ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human EP1 and 1.7 nM for mouse EP1. It effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer [1].

Prostaglandin Receptor, Others

Immunology/Inflammation, Others, GPCR/G Protein

216116

C22H30ClNO4S

440

C(NS(=O)(=O)C1=C(C)C=C(Cl)C=C1)[C@@H]2[C@@H](/C=C\CCCC(O)=O)C3CCC2CC3

-20°C

Ice Packs

Small Compound