ONO-8809 - CAS 123288-47-1

ONO-8809 is a thromboxane A2 receptor antagonist. ONO-8809 inhibited the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner. Macrophage accumulation and matrix metalloproteinase-9 (MMP-9) activity in the stroke-negative area in the contralateral cerebral cortex to the stroke lesion of salt-loaded SHRSP and 8-iso-PGF2alpha-treated SHRSP were significantly reduced by ONO-8809 treatment.

Others, Histamine Receptor

GPCR/G Protein, Immunology/Inflammation, Neuroscience, Others

123240

C30H46BrNO4S

596.66

C(NS(=O)(=O)C1=CC=C(Br)C=C1)[C@H]2[C@H](/C=C\CCCC(OCCCCCCCCCC)=O)[C@@]3(C[C@]2(CC3)[H])[H]

-20°C

Ice Packs

Small Compound