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Molfinity
OP-3633 - CAS 2102494-14-2
OP-3633 - CAS 2102494-14-2
SKU:MF-0033695-01
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Product Details
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Bioactivity
OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM) . OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.
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Target
Others, Glucocorticoid Receptor
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Related Pathways
Endocrinology/Hormones, Others
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CAS Number
2102478
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Molecular Formula
C30H39NO2
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Molecular Weight
445.64
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SMILES
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@]3(C5=CC=C(N(C)C)C=C5)[H])[C@@](C#CC)(O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound