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Molfinity

OPB-171775 - CAS 2131210-15-4

OPB-171775 - CAS 2131210-15-4

MF-0122335-01

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Product Details

  • Bioactivity

    OPB-171775 is a molecular glue that forms a ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12) . This compound induces cell death mediated by SLFN12 RNase, activates the SLFN12 RNase-associated GCN2 signaling pathway, and demonstrates antitumor activity.

  • CAS Number

    2131210-15-4

  • Molecular Formula

    C15H18F2N2O3

  • Molecular Weight

    312.31

  • SMILES

    FC1=C(C=CC(OCC(C)(C)O)=C1F)C=2[C@H](C)CC(=O)NN2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC