OPC-163493 - CAS 1644467-84-4

OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species) production. This compound demonstrates antidiabetic properties and cardiovascular benefits, including lowering blood pressure, prolonging survival, and enhancing renal function in a rat model of stroke/hypertension [1].

Mitochondrial Metabolism, Reactive Oxygen Species

Metabolism, Immunology/Inflammation, NF-κB

1644379

C14H8F3N5S

335.31

CC1=C(N=C(S1)C2=CC=C(C(F)(F)F)C=C2)C3=C(C#N)N=NN3

-20°C

Ice Packs

Small Compound