Opiranserin hydrochloride - CAS 1440796-75-7

Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50=0.87 μM) . It is development as an injectable agent for the treatment of postoperative pain.

GlyT, 5-HT Receptor, P2X Receptor

Neuroscience, GPCR/G Protein, Membrane transporter/Ion channel

1440714

0.9933

C21H35ClN2O5

430.97

Cl.CCCCOc1c(OC)cc(cc1OC)C(=O)NCC1(CCOCC1)N(C)C

-20°C

Ice Packs

Small Compound