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Orantinib - CAS 252916-29-3

Orantinib - CAS 252916-29-3

MF-0018354-01

$45.13 USD
$45.13 USD
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Product Details

  • Bioactivity

    Orantinib (NSC 702827), a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.

  • Target

    PDGFR, FGFR, VEGFR, Apoptosis

  • Related Pathways

    Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    252884

  • Purity

    >99.99%

  • Molecular Formula

    C18H18N2O3

  • Molecular Weight

    310.35

  • SMILES

    Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound