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ORIC-533 - CAS 2641306-62-7
ORIC-533 - CAS 2641306-62-7
SKU:MF-0121089-01
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Product Details
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Bioactivity
ORIC-533 is a selective CD73 inhibitor that is orally active and competes with AMP. It revitalizes the proliferation and activation of immunosuppressed CD8+ T cells and induces notable lysis and cell death in multiple myeloma cells within the bone marrow microenvironment [1].
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Target
CD73
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Related Pathways
Immunology/Inflammation
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CAS Number
2641306-62-7
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Molecular Formula
C20H29ClN9O9P
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Molecular Weight
605.93
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SMILES
O[C@H]1[C@H](N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3)O[C@H](CO[C@](COCC=5NN=NN5)(P(=O)(O)O)CO)[C@H]1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound