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Oritinib - CAS 2035089-28-0

Oritinib - CAS 2035089-28-0

MF-0014026-01

$135.50 USD
$135.50 USD
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Product Details

  • Bioactivity

    Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.

  • Target

    EGFR

  • Related Pathways

    JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    2035061

  • Purity

    0.9962

  • Molecular Formula

    C31H37N7O2

  • Molecular Weight

    539.67

  • SMILES

    COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c2CCCCn2c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound