Osimertinib - CAS 1421373-65-0

Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.

EGFR

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

1421308

>99.99%

C28H33N7O2

499.61

CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3

-20°C

Ice Packs

Small Compound