Osimertinib dimer - CAS 2564638-97-5

Osimertinibdimer is the dimer of Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutation-selective EGFR inhibitor, effectively suppressing L858R (IC50=12 nM) and L858R/T790M (IC50=1 nM) EGFR. It addresses resistance to EGFR inhibitors mediated by the T790M mutation in lung cancer.

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Others

2564536

C56H67N14O4

1000.22

O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1N(C)CC[N+](C)(C)CCC(=O)NC5=CC(NC=6N=CC=C(N6)C7=CN(C=8C=CC=CC78)C)=C(OC)C=C5N(C)CCN(C)C

-20°C

Ice Packs

Small Compound