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Osimertinib mesylate - CAS 1421373-66-1

Osimertinib mesylate - CAS 1421373-66-1

MF-0005768-01

$43.64 USD
$43.64 USD
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Product Details

  • Bioactivity

    Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.

  • Target

    EGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    1421306

  • Purity

    >99.99%

  • Molecular Formula

    C29H37N7O5S

  • Molecular Weight

    595.71

  • SMILES

    CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound