OTS964 - CAS 1338542-14-5

OTS964 is a potent, orally active compound that operates as a highly selective inhibitor of TOPK with an IC 50 of 28 nM [1]. Additionally, it demonstrates significant inhibitory action against cyclin-dependent kinase CDK11, specifically binding to CDK11B with a K d of 40 nM [2].

Others, Apoptosis, CDK, TOPK

Apoptosis, MAPK, Others, Cell Cycle/Checkpoint

1338523

C23H24N2O2S

392.51

OC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C([C@H](CN(C)C)C)C=C4

-20°C

Ice Packs

Small Compound