OXA-11 - CAS 1257994-15-2

OXA-11 (FAK-IN-16) is an orally active, selective focal adhesion kinase (FAK) inhibitor with antitumor activity. It inhibits FAK phosphorylation at tyrosine 397 in a dose-dependent manner and suppresses TOV21G tumor growth. It is used in cancer research.

FAK

Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

1257977

0.992

C37H49F3N7O5P

759.8

N(C1=C2C(=C(C=C1)[C@H]3CC[C@@H](CC3)N4CCN(C)CC4)CN(C)C2=O)C=5C(C(F)(F)F)=CN=C(NC6=C(OC)C=C(CP(OCC)(OCC)=O)C=C6)N5

-20°C

Ice Packs

Small Compound