Oxiconazole nitrate - CAS 64211-46-7

Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This disruption of membrane synthesis and integrity alters permeability, promotes loss of essential intracellular components, and inhibits fungal cell growth.

Cytochromes P450, Antifection, Antifungal, Antibiotic

Microbiology/Virology, Metabolism

64158

0.9973

C18H13Cl4N3O·HNO3

492.14

[N+](=O)([O-])O.C(=N\OCc1c(cc(cc1)Cl)Cl)(/c1c(cc(cc1)Cl)Cl)\Cn1ccnc1

-20°C

Ice Packs

Small Compound