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Oxidopamine hydrobromide - CAS 636-00-0
Oxidopamine hydrobromide - CAS 636-00-0
SKU:MF-0023175-01
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$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a widely used neurotoxin and an antagonist of the neurotransmitter dopamine. It selectively destroys dopaminergic neurons, promotes COX-2 activation, induces PGE2 synthesis, and stimulates the secretion of the pro-inflammatory cytokine IL-1β. It is commonly used to establish animal models of Parkinson’s disease (PD) .
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Target
Dopamine Receptor, Autophagy, Mitophagy
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Related Pathways
GPCR/G Protein, Autophagy, Neuroscience
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CAS Number
636-00-0
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Purity
0.9988
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Molecular Formula
C8H12BrNO3
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Molecular Weight
250.09
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SMILES
Br.NCCc1cc(O)c(O)cc1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound