Oxodipine - CAS 90729-41-2

Oxodipine, a dihydropyridine-type calcium antagonist, inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduced L-type Ca currents (I) with an IC of 0.24 μM, and against T-type Ca currents (I) with an IC of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs.

Calcium Channel

Membrane transporter/Ion channel, Metabolism

90686

0.9964

C19H21NO6

359.37

C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C3C(=CC=C2)OCO3

-20°C

Ice Packs

Small Compound