Oxypeucedanin - CAS 737-52-0

1. Oxypeucedanin ((+-) -Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD; therefore, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.

PI3K, ERK, COX, JNK, Potassium Channel, Apoptosis, Akt, NF-κB, p38 MAPK, NO Synthase

Immunology/Inflammation, Membrane transporter/Ion channel, NF-κB, MAPK, Apoptosis, Cytoskeletal Signaling, Neuroscience, PI3K/Akt/mTOR signaling

685

0.9971

C16H14O5

286.28

CC1(C)OC1COc1c2ccoc2cc2oc(=O)ccc12

-20°C

Ice Packs

Natural Product