P-CAB agent 2 - CAS 1978371-23-1

P-CAB Agent 2 is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor that effectively inhibits H+/K+-ATPase activity, showing an IC50 value of <100 nM. It also demonstrates inhibition of the hERG potassium channel with an IC50 value of 18.69 M, indicating no acute toxicity. P-CAB Agent 2 effectively curbs histamine-induced gastric acid secretion [1].

Others, Potassium Channel

Membrane transporter/Ion channel, Others

1978347

C22H25FN2O4S

432.51

S(=O)(=O)(N1C(=CC(CNC)=C1)C2=C(F)C=CC=C2)C3=CC(OCCCOC)=CC=C3

-20°C

Ice Packs

Small Compound