P-CAB agent 2 hydrochloride - CAS 2209911-80-6

P-CAB agent 2 hydrochloride is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor. It effectively inhibits H+/K+-ATPase activity, with an IC50 value of <100 nM, and targets the hERG potassium channel with an IC50 value of 18.69 μM. Moreover, P-CAB agent 2 hydrochloride demonstrates no acute toxicity and effectively inhibits histamine-induced gastric acid secretion [1].

Potassium Channel, Others

Membrane transporter/Ion channel, Others

2209825

C22H26ClFN2O4S

468.97

Cl.O=S(=O)(C=1C=CC=C(OCCCOC)C1)N2C=C(C=C2C=3C=CC=CC3F)CNC

-20°C

Ice Packs

Small Compound