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Molfinity

P-gb-IN-1 - CAS 2632874-49-6

P-gb-IN-1 - CAS 2632874-49-6

SKU:MF-0099449-01

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  • Bioactivity

    P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydrogen bonding with residues Asn 721 and Met 986. P-gb-IN-1 showed low toxicity in MCF-7/ADR cells.

  • Target

    P-gp

  • Related Pathways

    Neuroscience, Membrane transporter/Ion channel

  • CAS Number

    2632819

  • Purity

    0.9985

  • Molecular Formula

    C30H28N2O6

  • Molecular Weight

    512.55

  • SMILES

    O=C(NC=1C=CC(=CC1)C=2OC(=CC2)C(=O)N3CC4=CC(OC)=C(OC)C=C4CC3)C5=CC=C(OC)C=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound