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P-gb-IN-1 - CAS 2632874-49-6
P-gb-IN-1 - CAS 2632874-49-6
SKU:MF-0099449-01
Regular price
$91.63 USD
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$91.63 USD
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Product Details
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Bioactivity
P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydrogen bonding with residues Asn 721 and Met 986. P-gb-IN-1 showed low toxicity in MCF-7/ADR cells.
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Target
P-gp
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Related Pathways
Neuroscience, Membrane transporter/Ion channel
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CAS Number
2632819
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Purity
0.9985
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Molecular Formula
C30H28N2O6
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Molecular Weight
512.55
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SMILES
O=C(NC=1C=CC(=CC1)C=2OC(=CC2)C(=O)N3CC4=CC(OC)=C(OC)C=C4CC3)C5=CC=C(OC)C=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound