P-selectin antagonist 1 - CAS 2099111-75-6

Compound 11b, known as P-selectin antagonist 1, serves as an antagonist for both pan-selectin, with an IC50 of 82 μM, and E-selectin, with a KD of 0.91 μM.

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2099111-75-6

C56H71N5Na4O25S3

1402.34

CC[C@H]1C[C@@H](C(=O)NCCCc2cn(CCCC(=O)Nc3cc(S(=O)(=O)[O-])cc4cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c34)nn2)C[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@H](CC3CCCCC3)C(=O)[O-])[C@H]2OC(=O)c2ccccc2)[C@@H]1O[C@@H]1O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O.[Na+].[Na+].[Na+].[Na+]

-20°C

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