P11149 - CAS 164724-79-2

P11149, a derivative of Galanthamine, acts as a competitive, orally active, and selective AChE inhibitor with the ability to weakly penetrate the blood-brain barrier (BBB) . It demonstrates selective inhibition, exhibiting an IC50 of 1.3 μM for rat BChE/AChE, and shows central cholinergic activity, behavioral efficacy, and safety. P11149 is utilized in Alzheimer's disease research[1].

Cholinesterase (ChE), Others

Others, Neuroscience

164643

C27H34ClNO4

472.02

Cl.CN1CC[C@@]23C=C[C@H](O)C[C@@H]2Oc2c3c(C1)ccc2OC(=O)C12CC3CC(CC(C3)C1)C2

-20°C

Ice Packs

Small Compound