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P2Y14R antagonist 1 - CAS 2728291-29-8

P2Y14R antagonist 1 - CAS 2728291-29-8

MF-0100537-01

$41.39 USD
$41.39 USD
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Product Details

  • Bioactivity

    P2Y14R antagonist 1 (compound I-17) is a selective and potent P2Y14R antagonist (IC50=0.6 nM) with oral activity and good bioavailability that inhibits monosodium urate-induced inflammatory response in acute gouty arthritis by reducing inflammatory factor release via the NLRP3/GSDMD signaling pathway and cellular pyroptosis.

  • Target

    NOD-like Receptor (NLR), P2Y Receptor

  • Related Pathways

    Neuroscience, GPCR/G Protein, Immunology/Inflammation

  • CAS Number

    2728291-29-8

  • Purity

    0.9888

  • Molecular Formula

    C15H12BrN3O2

  • Molecular Weight

    346.18

  • SMILES

    O=C(NC=1C=CC=2N=CNC2C1)COC3=CC=C(Br)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound