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P38 Kinase inhibitor 8 - CAS 815595-25-6

P38 Kinase inhibitor 8 - CAS 815595-25-6

MF-0113887-01

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Product Details

  • Bioactivity

    P38 Kinase inhibitor 8 (Compound CCLXXVIII) is an orally active inhibitor targeting p38β and JNK2α2, with IC50 values of 6.3 nM and 53.6 nM, respectively. It has demonstrated anti-inflammatory effects in a rat model of collagen-induced arthritis.

  • Target

    P38 MAPK, JNK

  • Related Pathways

    MAPK

  • CAS Number

    815564

  • Molecular Formula

    C22H21FN6O2

  • Molecular Weight

    420.44

  • SMILES

    O=C(N1CCC(NC=2N=CC=C(N2)C3=C(N=C4OC=CN43)C5=CC=C(F)C=C5)CC1)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound