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P38-α MAPK-IN-9 - CAS 868272-50-8

P38-α MAPK-IN-9 - CAS 868272-50-8

MF-0113781-01

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Product Details

  • Bioactivity

    P38-α MAPK-IN-9 (Compound 25a) is a p38-α MAPK inhibitor with a Ki value of 0.057 nM. It effectively inhibits LPS-induced TNFα production in hPBMC cells, exhibiting an IC50 of 18 nM.

  • Target

    P38 MAPK

  • Related Pathways

    MAPK

  • CAS Number

    868214

  • Molecular Formula

    C19H20N8O2

  • Molecular Weight

    392.414

  • SMILES

    N#CC=1C(=NC(=NC1NC(C)C)N)NC2=CC(=CC=C2C)C(=O)NC3=NOC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound