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P38 MAPK-IN-9 - CAS 180869-17-4
P38 MAPK-IN-9 - CAS 180869-17-4
SKU:MF-0118932-01
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Product Details
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Bioactivity
P38 MAPK-IN-9 (Compound 15) is an orally active and highly selective inhibitor of the p38αMAP kinase (p38 MAPK), with an IC50 value of 9.6 nM. It holds potential for research into inflammatory diseases such as rheumatoid arthritis, septic shock, and chronic obstructive pulmonary disease.
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Target
P38 MAPK
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Related Pathways
MAPK
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CAS Number
180848
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Molecular Formula
C21H25FN6
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Molecular Weight
380.46
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SMILES
FC1=CC=C(C=C1)C=2N=CN(C2C=3N=C(N=CC3)NCC)C4CCN(C)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound