P53-MDM2-IN-5 - CAS 2750075-06-8

P53-MDM2-IN-5 (compound 5a), a robust p53-MDM2 inhibitor, effectively induces apoptosis, autophagy, and DNA damage. It also causes cell cycle arrest at the S and G2/M phases and demonstrates anti-tumor activity.

MDM-2/p53, Autophagy, Apoptosis

Apoptosis, Autophagy

2750075-06-8

C33H37Cl4F2N5O6Pt

974.57

C(#N)[C@]1([C@H]([C@H](C(NC2=C(OC)C=C(C([O-][Pt+4]([O-]C(C)=O)([Cl-])([Cl-])([NH3])[NH3])=O)C=C2)=O)N[C@H]1CC(C)(C)C)C3=C(F)C(Cl)=CC=C3)C4=C(F)C=C(Cl)C=C4

-20°C

Ice Packs

Small Compound