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Molfinity

Pabinafusp alfa - CAS 2140211-48-7

Pabinafusp alfa - CAS 2140211-48-7

MF-0099986-01

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Product Details

  • Bioactivity

    Pabinafusp alfa (JR-141), a transferrin receptor-targeting antibody fusing Iduronate 2-sulfatase with an anti-human transferrin receptor antibody, penetrates the blood-brain barrier and inhibits heparan sulfate (HS) accumulation within the central nervous system of mucopolysaccharidosis II (MPS II) mice. It enhances cognitive function and protects against neuronal damage in the central nervous system [1].

  • Target

    Others

  • Related Pathways

    Others

  • CAS Number

    2140211-48-7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Inhibitory Antibodies