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Pacritinib hydrochloride - CAS 1228923-43-0
Pacritinib hydrochloride - CAS 1228923-43-0
SKU:MF-0043738-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM), and can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis (MF) .
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Target
Others, JAK
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Related Pathways
Others, JAK/STAT signaling, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Stem Cells
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CAS Number
1228880
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Molecular Formula
C28H32N4O3.xClH
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound