PAIR2 - CAS 2771006-54-1

PAIR2 is a potent, selective partial antagonist of IRE1α RNase, effectively occupying the ATP-binding site of IRE1α in cells. This action prevents a potent KIRA from inhibiting XBP1 splicing [1].

Others, IRE1

Cell Cycle/Checkpoint, Others

2770951

C27H26F4N6O3S

590.59

O(C=1C2=C(C(NS(CC(F)(F)F)(=O)=O)=C(F)C1C)C=CC=C2)C3=C(C=CC=N3)C4=NC(N[C@H]5CCCNC5)=NC=C4

-20°C

Ice Packs

Small Compound