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Palbociclib - CAS 571190-30-2

Palbociclib - CAS 571190-30-2

SKU:MF-0034860-01

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  • Bioactivity

    Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-negative breast cancer.

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    571158

  • Purity

    0.999

  • Molecular Formula

    C24H29N7O2

  • Molecular Weight

    447.53

  • SMILES

    O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCNCC4)N2)C5CCCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound