Palbociclib orotate - CAS 2757498-64-7

Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively. This compound demonstrates potent anti-proliferative effects and induces cell cycle arrest in cancer cells, applicable in research concerning HR-positive, HER2-negative breast cancer, and hepatocellular carcinoma [1] [3] [4].

CDK

Cell Cycle/Checkpoint

2757427

C29H33N9O6

603.63

-20°C

Ice Packs

Small Compound