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Palbociclib-propargyl - CAS 2366269-23-8
Palbociclib-propargyl - CAS 2366269-23-8
SKU:MF-0151022
Regular price
$92.44 USD
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Sale price
$92.44 USD
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Product Details
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Bioactivity
Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].
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Target
Others, Ligands for Target Protein for PROTAC
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Related Pathways
Others, PROTAC
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CAS Number
2366238
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Molecular Formula
C27H31N7O2
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Molecular Weight
485.58
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SMILES
CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC#C)CC3)nc2n(C2CCCC2)c1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC