Palifosfamide tromethamine - CAS 1070409-31-2

Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide.

Others, DNA Alkylator/Crosslinker

Others, DNA Damage/DNA Repair

1070376

C8H22Cl2N3O5P

342.16

O=P(O)(NCCCl)NCCCl.OCC(N)(CO)CO

-20°C

Ice Packs

Small Compound